The National Centre of Personalised Endocrine Medicine
A team of the National Medical Research Centre of Endocrinology has been engaged to create the National Centre for Personalized Medicine of Endocrine Diseases. This is logical, as personalized medicine is a concept that has long been implemented in the centre of endocrinology.
Founded by scientist I.I. Dedov, his model of personalized preventive treatment is in line with global goals - saving the people, minimising the risks of preventable disability and mortality due to diabetes mellitus and endocrine tumors, preserving the intellectual and reproductive potential of the Russian Federation, and ensuring the duration and quality of life of fellow citizens.
Founded by scientist I.I. Dedov, his model of personalized preventive treatment is in line with global goals - saving the people, minimising the risks of preventable disability and mortality due to diabetes mellitus and endocrine tumors, preserving the intellectual and reproductive potential of the Russian Federation, and ensuring the duration and quality of life of fellow citizens.
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Goals and Objectives
Goal 1
To create an analytical system for predicting the development of complications and outcomes of the course of endocrine diseases using high-tech diagnostic algorithms, artificial intelligence technology and big data analysis on the basis of the endocrinopathy database.
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Goal 2
To develop progressive technologies for personalized diagnosis of endocrine and oncoendocrine diseases (diabetes mellitus, congenital dysfunction of the adrenal cortex, autoimmune polyglandular syndromes, various forms of thyroid cancer, parathyroid tumors, multiple endocrine neoplasia syndromes) based on a platform developed using an artificial intelligence platform that unites clinical, genomic, metabolomic, and immuno-histochemical parameters.
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Goal 3
To develop progressive methods of therapy for endocrine diseases, primarily diabetes mellitus, orphan life-threatening (congenital dysfunction of the adrenal cortex (viril and salt-losing forms of adrenogenital syndrome)) and oncoendocrine pathologies (multiple endocrine and thyroid tumors) glands) on the basis of modern radionuclide, genetic, and cellular technologies.
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Leading Researchers
President of the Centre, Member of the Presidium of the Russian Academy of Sciences, Academician, Doctor of Medical Sciences, Professor, President of the Russian Association of Endocrinologists, chief freelance specialist endocrinologist of the Ministry of Health of Russia.
Director of the Centre, Corresponding Member of the Russian Academy of Sciences, Professor, Doctor of Medicine, doctor of the highest qualification category
Director of the Institute of Personalized Medicine, PhD in Biological Sciences
PhD, Harvard Medical School, USA, Genetics
PhD, Schepens Eye Research Institute, USA, Ophthalmology
PhD, RIKEN, Japan, Hematology, Genetics
Doctor of Biological Sciences, Vienna Medical University, Austria, Biochemistry and Molecular Biology
PhD, Uppsala University, Sweden, Molecular Biology, Biotechnology and Cell Biology
PhD, Ph.D., RIKEN, Japan, KFU, Russia, Biochemistry, Molecular Genetics, Genomics
PhD, Doctor of Physics and Mathematics, Mayo Clinic, USA, Computational Biology
Partners
Current Projects
Therapy of monogenic forms of diabetes mellitus using a biomedical cell product
Therapy for autoimmune diabetes mellitus with a biomedical cell product
Therapy for hypoparathyroidism with a biomedical cell product
Study of molecular genetic mechanisms of PTG carcinogenesis using new cellular models and identification of potential targets of therapeutic action
AAV mediated therapy of hereditary endocrinopathies, primarily congenital dysfunction of the adrenal cortex (viril and salt-wasting forms of adrenogenital syndrome) and other forms of adrenal insufficiency
Discovery of targets for the therapeutic targeting of bone tissue in primary hyperparathyroidism
Development of a program for the timely diagnosis of immune diseases of the endocrine system (thyroid pathologies, hypophysitis, adrenal insufficiency, diabetes mellitus, hypogonadism) in cancer patients
Development of a program for the timely diagnosis of immune diseases of the endocrine system (thyroid pathologies, hypophysitis, adrenal insufficiency, diabetes mellitus, hypogonadism) in cancer patients
Advanced technologies for the personalized diagnosis of endocrine tumors (various types of thyroid cancer, neuroendocrine tumors, including pheochromocytomas / paragangliomas and multiple endocrine tumors) through molecular genetics
Molecular genetic characterization and molecular imaging of neuroendocrine tumors (ACTH-ectopic syndrome, tumors producing FGF23, thyroid cancer)
Preimplantation genetic diagnosis in individuals with monogenic endocrinopathies
Radio-targeted therapy with theranostics
Information and analytical platform for the accumulation of data on patients with endocrinopathies
Creation of a database of ethnically-oriented clinical-demographic, molecular-genetic, and post-genomic markers of the development of type 1 diabetes mellitus (DM) and non-immune forms of diabetes in children and adolescents, including "nuclear" families, with identification of individual risks and the development of a personalized algorithm to calculate risks for different ethnic groups
Laboratories
Cell Technology Laboratory
Laboratory of Molecular Onco-Endocrinology
Laboratory of Metabolic and Proteomic Research
Laboratory of Microbiota
Molecular Imaging and Theranostics Laboratory
Laboratory of General, Molecular and Population Genetics
Genome Editing Laboratory
Laboratory of Digital Technologies and AI
The Team
Events
Vacancies
Researcher
Laboratory of Molecular Oncoendocrinology, National Center for Personalized Medicine of Endocrine Diseases
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Address: 117036, Moscow,
Dmitry Ulyanov St, 11
Akademicheskaya Station
Dmitry Ulyanov St, 11
Akademicheskaya Station
